Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 13/20 | 0.45 |
| ▸ | PLAU | P00749 | 12/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563916 | 0.91 | TMPRSS6 (0.47) | HPNPLAUMEN1ALDH1A1MAPT | |
| SCHEMBL6563461 | 0.90 | PRSS1 (0.49) | HPNPLAUPRSS1 | |
| SCHEMBL7670899 | 0.86 | PRSS1 (0.43) | HPNPLAUALDH1A1PRSS1 | |
| SCHEMBL6563318 | 0.81 | BCHE (0.49) | MEN1ALDH1A1MAPTKMT2ACA12 | |
| SCHEMBL8558497 | 0.79 | GAA (0.61) | HPNPLAUMEN1ALDH1A1MAPT | |
| SCHEMBL6561878 | 0.77 | PRSS1 (0.43) | PRSS1 | |
| SCHEMBL6563625 | 0.77 | PRSS1 (0.43) | ALDH1A1PKMPRSS1 | |
| SCHEMBL6563743 | 0.77 | PRSS1 (0.43) | PRSS1 | |
| SCHEMBL7674188 | 0.76 | EGLN1 (0.44) | PLAUPRSS1 | |
| SCHEMBL6563675 | 0.75 | F10 (0.47) | MEN1ALDH1A1KMT2APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |