Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | AIP | O00170 | 1/20 | 0.47 |
| ▸ | SGTA | O43765 | 1/20 | 0.47 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.47 |
| ▸ | STIP1 | P31948 | 1/20 | 0.47 |
| ▸ | PPP5C | P53041 | 1/20 | 0.47 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003174 | 0.77 | ALDH1A1 (0.72) | MAPTHSD17B10ALDH1A1POLBMEN1 | |
| SCHEMBL1862342 | 0.70 | ALDH1A1 (0.72) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL27075492 | 0.67 | HSD17B10 (0.67) | MAPTHSD17B10ALDH1A1POLBMEN1 | |
| SCHEMBL6464495 | 0.66 | ADORA2A (0.56) | MAPTHSD17B10ALDH1A1POLBMEN1 | |
| SCHEMBL6317632 | 0.65 | ADORA2A (0.53) | MAPTHSD17B10ALDH1A1POLBMEN1 | |
| SCHEMBL6412764 | 0.64 | LMNA (0.61) | HSD17B10ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3177576 | 0.63 | LMNA (0.77) | HSD17B10ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL3869753 | 0.63 | MAPT (0.52) | MAPTHSD17B10ALDH1A1POLBMEN1 | |
| SCHEMBL7003055 | 0.63 | AIP (0.74) | MAPTHSD17B10ALDH1A1POLBMEN1 | |
| Diethylamine SCHEMBL27851494 | 0.63 | GAA (0.49) | MAPTHSD17B10ALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |