SCHEMBL7669735

SCHEMBL7669735

COC(=O)C1C(c2ccc(OCc3ccccc3)c(OCc3ccccc3)c2)OC(=O)N1C(C)c1cccc2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYB P10242 1/20 0.38
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SMPD1 P17405 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
APP P05067 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CASR P41180 1/20 0.36
CASP1 P29466 2/20 0.36
F2 P00734 1/20 0.36
F10 P00742 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8054619 0.89 LTA4H (0.41) ALDH1A1RAB9ASMN1; SMN2CASP1CASP3
SCHEMBL7674327 0.87 CASR (0.39) ALDH1A1KMT2AKDM4EHPGDRAB9A
SCHEMBL7670104 0.87 CASR (0.39) ALDH1A1KMT2AKDM4EHPGDRAB9A
SCHEMBL7671921 0.84 CASR (0.35) KMT2AMEN1CASR
SCHEMBL7672054 0.84 HSD11B1 (0.39) KMT2AMEN1GAACASR
SCHEMBL7667907 0.84 HSD11B1 (0.39) KMT2AMEN1GAACASR
SCHEMBL7665896 0.82 APP (0.41) HPGDRAB9ASMPD1HDAC1HDAC8
SCHEMBL7685510 0.81 CASP1 (0.39) GAACASRCASP1
SCHEMBL7665900 0.80 KDM4E (0.41) ALDH1A1KDM4EHPGDRAB9ANPSR1
SCHEMBL7661213 0.80 KDM4E (0.41) ALDH1A1KDM4EHPGDRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414160-B1 REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed
EP-1000937-A1 PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS UBE INDUSTRIES LIMITED (JP) 2000-05-17 EP disclosed