Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489297 | 0.90 | MAPT (0.41) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL16836769 | 0.80 | ALDH1A1 (0.47) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL29040001 | 0.78 | UBE2N (0.60) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL7672020 | 0.77 | HCAR2 (0.41) | ALDH1A1MAPK1KMT2AMEN1GABRP | |
| SCHEMBL21678973 | 0.77 | ALDH1A1 (0.51) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL28050769 | 0.77 | CA12 (0.43) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL16836849 | 0.75 | MAPT (0.42) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL2743308 | 0.75 | NPC1 (0.46) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL2596908 | 0.74 | NPC1 (0.46) | MAPTNPC1ALDH1A1TP53XBP1 | |
| SCHEMBL17173720 | 0.73 | MAPT (0.51) | MAPTNPC1ALDH1A1TP53XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437139-B1 | OMEPRAZOLE, LANSOPRAZOLE AND PANTOPRAZOLE INTERMEDIATES; FREE RADICAL REACTION WITH ETHYL PYRUVATE TO FUNCTIONALIZE THE 2-POSITION | PDI-RESEARCH LABORATORIES, INC. (CA) | 2002-08-20 | — | — | US | disclosed |
| WO-1999033807-A2 | SYNTHESIS OF PHARMACEUTICALLY USEFUL PYRIDINE DERIVATIVES (INTERMEDIATES) EMPLOYING FREE RADICAL SUBSTITUTION REACTIONS TO FUNCTIONALIZE THE 2-POSITION OF THE PYRIDINE | PDI-RESEARCH LABORATORIES, INC. (CA) | 1999-07-08 | — | — | WO | disclosed |
| US-5616713-A | Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 1997-04-01 | — | — | US | disclosed |