Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222305 | 0.82 | HCAR2 (0.40) | HCAR2KMOTDP1MEN1KMT2A | |
| SCHEMBL7788149 | 0.81 | GABRP (0.38) | HCAR2KMOMEN1KMT2AALDH1A1 | |
| SCHEMBL10428608 | 0.79 | KMT2A (0.33) | HCAR2KMOTDP1MEN1KMT2A | |
| SCHEMBL1769880 | 0.78 | KDM4E (0.39) | HCAR2KMOMEN1KMT2AALDH1A1 | |
| SCHEMBL7666078 | 0.78 | LDHA (0.36) | HCAR2KMOTDP1MEN1KMT2A | |
| SCHEMBL28330033 | 0.77 | HCAR2 (0.39) | HCAR2KMOTDP1MEN1KMT2A | |
| SCHEMBL27566700 | 0.77 | HCAR2 (0.36) | HCAR2KMOTDP1MEN1KMT2A | |
| SCHEMBL7669745 | 0.77 | MAPT (0.48) | TDP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22890818 | 0.77 | LRRK2 (0.48) | HCAR2KMOTDP1MEN1KMT2A | |
| SCHEMBL29644137 | 0.77 | LRRK2 (0.48) | HCAR2KMOTDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437139-B1 | OMEPRAZOLE, LANSOPRAZOLE AND PANTOPRAZOLE INTERMEDIATES; FREE RADICAL REACTION WITH ETHYL PYRUVATE TO FUNCTIONALIZE THE 2-POSITION | PDI-RESEARCH LABORATORIES, INC. (CA) | 2002-08-20 | — | — | US | disclosed |
| WO-1999033807-A2 | SYNTHESIS OF PHARMACEUTICALLY USEFUL PYRIDINE DERIVATIVES (INTERMEDIATES) EMPLOYING FREE RADICAL SUBSTITUTION REACTIONS TO FUNCTIONALIZE THE 2-POSITION OF THE PYRIDINE | PDI-RESEARCH LABORATORIES, INC. (CA) | 1999-07-08 | — | — | WO | disclosed |