SCHEMBL16836769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7669745	0.80	MAPT (0.48)	ALDH1A1MEN1KMT2AMAPTGABRP
	SCHEMBL17512466	0.77	CYP1A2 (0.46)	ALDH1A1MEN1KMT2AMAPTKDM4E
	SCHEMBL28050636	0.77	ALDH1A1 (0.47)	ALDH1A1MEN1KMT2AMAPTGABRP
	SCHEMBL16836849	0.75	MAPT (0.42)	ALDH1A1MEN1KMT2AMAPTGABRP
	SCHEMBL392723	0.74	ALDH1A1 (0.49)	ALDH1A1MEN1KMT2AMAPTGABRP
	SCHEMBL24131085	0.73	CYP1A2 (0.46)	ALDH1A1MEN1KMT2AMAPTKDM4E
	SCHEMBL18404967	0.73	ALDH1A1 (0.47)	ALDH1A1MEN1KMT2AMAPTKDM4E
	SCHEMBL28634780	0.73	BRD4 (0.49)	ALDH1A1MEN1KMT2AMAPTKDM4E
	SCHEMBL13622778	0.73	ALDH1A1 (0.44)	ALDH1A1MEN1KMT2AMAPTGABRA1
	SCHEMBL25765775	0.72	KDM4E (0.46)	ALDH1A1KMT2AMAPTGABRPGABRD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.