Sugi Predict

Sugi Predict / Compounds / SCHEMBL7670278

SCHEMBL7670278

SCHEMBL7670278

C[S+]([O-])c1c(C(N)=S)nn(-c2ccc(C(F)(F)F)cc2Cl)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.42
▸ PHGDH O43175 1/20 0.38
▸ GABRP O00591 13/20 0.35
▸ GABRD O14764 13/20 0.35
▸ GABRA1 P14867 13/20 0.35
▸ GABRB1 P18505 13/20 0.35
▸ GABRG2 P18507 13/20 0.35
▸ GABRB3 P28472 13/20 0.35
▸ GABRA5 P31644 13/20 0.35
▸ GABRA3 P34903 13/20 0.35
▸ GABRA2 P47869 13/20 0.35
▸ GABRB2 P47870 13/20 0.35
▸ GABRA4 P48169 13/20 0.35
▸ GABRE P78334 13/20 0.35
▸ GABRA6 Q16445 13/20 0.35
▸ GABRG1 Q8N1C3 13/20 0.35
▸ GABRG3 Q99928 13/20 0.35
▸ GABRQ Q9UN88 13/20 0.35
▸ MAPT P10636 1/20 0.34
▸ MARS1 P56192 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7024380 0.89 GABRP (0.34) ALDH1A1PHGDHGABRPGABRDGABRA1
SCHEMBL7024373 0.85 GABRP (0.35) PHGDHGABRPGABRDGABRA1GABRB1
SCHEMBL7667746 0.85 GABRP (0.49) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL7670283 0.82 GABRP (0.42) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7673514 0.81 GABRP (0.46) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL7029141 0.80 GABRP (0.43) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL7028046 0.75 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL33214 0.74 GABRP (0.52) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL7675454 0.74 GABRP (0.46) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL7243490 0.74 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020016468-A1 PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 2002-02-07 — — US claimed
EP-0948487-A1 PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 1999-10-13 — — EP claimed
WO-1998028279-A1 PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 1998-07-02 — — WO claimed
US-20020016468-A1 PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 2002-02-07 — — US disclosed
EP-0948487-A1 PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 1999-10-13 — — EP disclosed
WO-1998028279-A1 PESTICIDAL 1-ARYL AND PYRIDYLPYRAZOLE DERIVATIVES RHONE-POULENC AGROCHIMIE (FR) 1998-07-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020016468-A1 PESTICIDAL 1-ARYLPYRAZOLE DERIVATIVES DDT, NAT1, CYP2E1 ALDH1A1 361/4885PHGDH 3079/4885GABRP 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.