Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657551 | 0.84 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL24568366 | 0.83 | LMNA (0.60) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7667035 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7666766 | 0.79 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL14540710 | 0.78 | LMNA (0.72) | LMNACHRNB2CHRNA4ALDH1A1RIPK1 | |
| SCHEMBL27294624 | 0.77 | CHRNB2 (0.61) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7664885 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7670854 | 0.77 | SMN1; SMN2 (0.54) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7667297 | 0.76 | MAPT (0.59) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7669180 | 0.75 | LMNA (0.48) | SMN1; SMN2LMNACHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407248-B1 | INSECTICIDES, MITICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| US-6124297-A | COMBATTING INSECTS OR MITES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| US-5935981-A | INSECTICIDAL/MITICIDAL ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-10 | — | — | US | disclosed |
| US-5849768-A | α-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0529680-B1 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-05-13 | — | — | EP | disclosed |
| EP-0302389-B1 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1993-12-22 | — | — | EP | disclosed |
| US-5214152-A | Insecticides, miticides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0529680-A2 | Intermediates, their production and their use for preparing alpha-unsaturated amines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5175301-A | Insecticide, miticide, pesticide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-12-29 | — | — | US | disclosed |
| EP-0509559-A2 | Alpha-unsaturated amines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| EP-0302389-A2 | Alpha-unsaturated amines, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-08 | — | — | EP | disclosed |