SCHEMBL7671397

SCHEMBL7671397

OC[CH]Cc1ccc(Br)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 4/20 0.42
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TAAR1 Q96RJ0 3/20 0.39
HTR2A P28223 1/20 0.39
CYP2A6 P11509 1/20 0.38
TGM2 P21980 1/20 0.37
ALOX15 P16050 1/20 0.36
AGER Q15109 1/20 0.35
EPHX1 P07099 1/20 0.35
PYCR1 P32322 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1043663 0.78 CA2 (0.48) IDO1MEN1KMT2ATAAR1ALOX15
SCHEMBL2121986 0.76 IDO1 (0.42) IDO1MEN1KMT2ATAAR1CYP2A6
SCHEMBL118087 0.75 MAOB (0.55) IDO1
Hydrochloric Acid SCHEMBL7197955 0.74 TAAR1 (0.48) IDO1MEN1KMT2ATAAR1HTR2A
SCHEMBL6480564 0.74 ALDH1A1 (0.38) IDO1MEN1KMT2ATAAR1HTR2A
SCHEMBL6480557 0.74 ALDH1A1 (0.38) IDO1MEN1KMT2ATAAR1HTR2A
SCHEMBL20103 0.72 CYP2A6 (0.44) IDO1MEN1KMT2ATAAR1HTR2A
SCHEMBL6017301 0.72 CYP2A6 (0.44) IDO1MEN1KMT2ATAAR1HTR2A
SCHEMBL13673478 0.72 CYP2A6 (0.44) IDO1MEN1KMT2ATAAR1HTR2A
SCHEMBL24042960 0.71 IDO1 (0.43) IDO1MEN1KMT2ATAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340759-B1 ANTISPASMODIC AGENTS EISAI CO., LTD. (JP) 2002-01-22 US disclosed