Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666059 | 0.90 | HIF1A (0.41) | HIF1AEPAS1KMT2APDE4DMEN1 | |
| SCHEMBL7667651 | 0.86 | CYP2D6 (0.39) | KMT2AATMMAPTHSD17B10MAPK1 | |
| SCHEMBL7672014 | 0.86 | CYP2D6 (0.39) | KMT2AATMMAPTHSD17B10MAPK1 | |
| SCHEMBL7670104 | 0.84 | CASR (0.39) | HIF1AEPAS1KMT2AMEN1KDM4E | |
| SCHEMBL7674327 | 0.84 | CASR (0.39) | HIF1AEPAS1KMT2AMEN1KDM4E | |
| SCHEMBL7671107 | 0.82 | EDNRB (0.44) | KDM4EALDH1A1ACHEGAANPC1 | |
| SCHEMBL7668422 | 0.79 | PDE4D (0.35) | HIF1AEPAS1KMT2AATMPDE4D | |
| SCHEMBL7674321 | 0.78 | CHRM4 (0.44) | KMT2AATMMEN1ALDH1A1NPC1 | |
| SCHEMBL7665863 | 0.78 | CYP2D6 (0.40) | KMT2AALDH1A1MAPTHSD17B10GAA | |
| SCHEMBL7672498 | 0.78 | MAPT (0.39) | KMT2AATMMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414160-B1 | REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST | UBE INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1000937-A1 | PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS | UBE INDUSTRIES LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |