Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 4/20 | 0.44 |
| ▸ | EDNRA | P25101 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672634 | 0.91 | EDNRB (0.43) | EDNRBEDNRARAB9ATSHRGAA | |
| SCHEMBL7661213 | 0.86 | KDM4E (0.41) | EDNRBEDNRARAB9AGAAKDM4E | |
| SCHEMBL7665900 | 0.86 | KDM4E (0.41) | EDNRBEDNRARAB9AGAAKDM4E | |
| SCHEMBL7672014 | 0.84 | CYP2D6 (0.39) | TSHR | |
| SCHEMBL7667651 | 0.84 | CYP2D6 (0.39) | TSHR | |
| SCHEMBL7671908 | 0.82 | HIF1A (0.43) | RAB9AGAAKDM4EACHESMN1; SMN2 | |
| SCHEMBL7672624 | 0.82 | ALDH1A1 (0.39) | RAB9ATSHRKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7667659 | 0.78 | KDM4E (0.38) | RAB9ATSHRGAAKDM4ESMN1; SMN2 | |
| SCHEMBL7674321 | 0.76 | CHRM4 (0.44) | RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7672498 | 0.76 | MAPT (0.39) | TSHRGAAALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414160-B1 | REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST | UBE INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1000937-A1 | PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS | UBE INDUSTRIES LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |