Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7673066 | 0.90 | CYP1A2 (0.38) | MAPTHSD17B10MAPK1CYP1A2TSHR | |
| SCHEMBL7665863 | 0.87 | CYP2D6 (0.40) | MAPTHSD17B10MAPK1CYP1A2TSHR | |
| SCHEMBL7674192 | 0.87 | MAPT (0.39) | MAPTHSD17B10MAPK1CYP1A2TSHR | |
| SCHEMBL7672014 | 0.86 | CYP2D6 (0.39) | MAPTHSD17B10MAPK1CYP1A2TSHR | |
| SCHEMBL7667651 | 0.86 | CYP2D6 (0.39) | MAPTHSD17B10MAPK1CYP1A2TSHR | |
| SCHEMBL7673238 | 0.82 | KCNA5 (0.39) | MAPTHSD17B10MAPK1CYP1A2TSHR | |
| SCHEMBL7674018 | 0.81 | HSD11B1 (0.41) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7671032 | 0.81 | HSD11B1 (0.41) | ALDH1A1LMNAGAAKMT2AMEN1 | |
| SCHEMBL7674117 | 0.80 | KCNA5 (0.40) | TSHRALDH1A1KCNA5KMT2ANR3C2 | |
| SCHEMBL7669764 | 0.78 | ALDH1A1 (0.44) | HSD17B10CYP2D6CYP3A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414160-B1 | REACTING 5-ALKOXY-2(3H)OXAZOLONE COMPOUND WITH ALDEHYDE COMPOUND IN PRESENCE OF LEWIS ACID CATALYST | UBE INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-1000937-A1 | PROCESS FOR PRODUCING 4-ALKOXYCARBONYL-2-OXAZOLIDINONE COMPOUNDS | UBE INDUSTRIES LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |