Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676030 | 0.84 | ALDH1A1 (0.72) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL6466443 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL30567082 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL25374549 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL5592136 | 0.78 | ALDH1A1 (0.63) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL8431899 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL5819225 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL21800166 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL119177 | 0.76 | KMT2A (0.77) | ALDH1A1LMNAHTTMAPTKDM4E | |
| SCHEMBL8431893 | 0.75 | ALDH1A1 (0.60) | ALDH1A1LMNAHTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407245-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | disclosed |
| US-20010012897-A1 | Substituted thiopyridines | HAMPRECHT GERHARD (DE) | 2001-08-09 | — | — | US | disclosed |
| US-6262273-B1 | REACTING A3-CHLORO-2-HALOPYRIDINE WITH THIO COMPOUND IN PRESENCE OF TRIFLUOROACETIC ACID OR PERCHLORIC ACID TO GIVE PYRIDINE THIOETHER COMPOUND WHICH IS OXIDIZED TO GIVE THIOPYRIDINE COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-17 | — | — | US | disclosed |
| US-6191280-B1 | REACTING SUBSTITUTED 2-HALOPYRIDINE DERIVATIVE WITH A THIO COMPOUND IN PRESENCE OF COPPER CATALYST TO GIVE A PYRIDINE THIOETHER, AND THEN OXIDIZING THE THIOETHER INTERMEDIATE TO FORM SULFOXIDE OR SULFONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| US-6169184-B1 | REACTING SUBSTITUTED PYRIDINE WITH SPECIFIED ARYL COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-02 | — | — | US | disclosed |
| EP-0984935-A1 | METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-15 | — | — | EP | disclosed |
| EP-0934275-A1 | SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-11 | — | — | EP | disclosed |
| EP-0931068-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998054139-A1 | METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-03 | — | — | WO | disclosed |
| WO-1998011072-A1 | SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |
| WO-1998011069-A1 | PROCESS FOR THE PRODUCTION OF SUBSTITUTED PHENYLPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012897-A1 | Substituted thiopyridines | CBR1, CLIC1, CBR3 | ALDH1A1 294/4885LMNA 1928/4885HTT 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.