Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757842 | 0.88 | KDM4E (0.59) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| Bromide SCHEMBL6849900 | 0.86 | KDM4E (0.57) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL28857264 | 0.85 | KDM4E (0.55) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL14036676 | 0.82 | NPSR1 (0.60) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL6213988 | 0.80 | LMNA (0.53) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL3414758 | 0.80 | CA1 (0.51) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL27321433 | 0.80 | KDM4E (0.59) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL7586997 | 0.78 | KDM4E (0.52) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL6633938 | 0.77 | CA1 (0.56) | KDM4ESMN1; SMN2GAAMPOHIF1A | |
| SCHEMBL1799299 | 0.77 | KDM4E (0.65) | KDM4ESMN1; SMN2GAAMPOHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395904-B1 | HYDROXYAMIDE COMPLEXES WITH IRON | YALE UNIVERSITY | 2002-05-28 | — | — | US | disclosed |
| WO-1999010357-A1 | BINUCLEAR NON-HEME IRON CATALYSTS | YALE UNIVERSITY (US) | 1999-03-04 | — | — | WO | disclosed |