Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 5/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.53 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PGAM1 | P18669 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21244029 | 0.90 | ALDH1A1 (0.54) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL29978305 | 0.90 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043775 | 0.90 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL21244028 | 0.83 | MCOLN3 (0.60) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL29978358 | 0.78 | L3MBTL1 (0.79) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043676 | 0.78 | L3MBTL1 (0.79) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL21244032 | 0.77 | MCOLN3 (0.58) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL21244033 | 0.77 | MCOLN3 (0.58) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23044095 | 0.76 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 | |
| SCHEMBL23043601 | 0.76 | MCOLN3 (0.76) | MCOLN3L3MBTL1PKMMCOLN2MCOLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1072587-A1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-01-31 | — | — | EP | disclosed |