Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264288 | 0.83 | IRAK4 (0.63) | IRAK4CTNNB1MAPTHTTLMNA | |
| SCHEMBL29423358 | 0.83 | IRAK4 (0.63) | IRAK4CTNNB1MAPTHTTLMNA | |
| Potassium Ion SCHEMBL1002905 | 0.82 | KDM4E (0.44) | IRAK4CTNNB1MAPTHTTLMNA | |
| SCHEMBL730840 | 0.82 | KDM4E (0.48) | IRAK4CTNNB1MAPTHTTSLC6A3 | |
| Potassium Ion SCHEMBL29619648 | 0.82 | KDM4E (0.44) | IRAK4CTNNB1MAPTHTTLMNA | |
| SCHEMBL5459 | 0.82 | KDM4E (0.61) | MAPTHTTLMNAMEN1KMT2A | |
| SCHEMBL31174577 | 0.82 | IRAK4 (0.61) | IRAK4CTNNB1MAPTHTTLMNA | |
| SCHEMBL4881322 | 0.82 | IRAK4 (0.61) | IRAK4CTNNB1MAPTHTTLMNA | |
| Hydrochloric Acid SCHEMBL3144924 | 0.82 | IRAK4 (0.61) | IRAK4CTNNB1MAPTHTTLMNA | |
| Hydrochloric Acid SCHEMBL4374712 | 0.82 | IRAK4 (0.61) | IRAK4CTNNB1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864837-B | Alkoxysilylamine compounds and uses thereof | 弗萨姆材料美国有限责任公司 | 2017-08-25 | — | — | CN | disclosed |
| CN-105801616-A | Alkoxysilylamine compounds and applications thereof | 气体产品与化学公司 | 2016-07-27 | — | — | CN | disclosed |
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | disclosed |
| US-5480631-A | Radioiodinated benzamines and method of their use as radioimaging | VANDERBILT UNIVERSITY (US) | 1996-01-02 | — | — | US | disclosed |