SCHEMBL5459

SCHEMBL5459

COOc1ccccc1C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.61
HPGD P15428 7/20 0.61
HSD17B10 Q99714 6/20 0.61
HTT P42858 2/20 0.61
ALDH1A1 P00352 9/20 0.60
HMGB1 P09429 2/20 0.60
NAPRT Q6XQN6 2/20 0.60
ESR1 P03372 1/20 0.60
ITGB3 P05106 1/20 0.60
ITGA2B P08514 1/20 0.60
TSHR P16473 1/20 0.60
GGT1 P19440 1/20 0.60
PTGS1 P23219 1/20 0.60
PTGS2 P35354 1/20 0.60
BLM P54132 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
USP2 O75604 1/20 0.53
PDE3A Q14432 1/20 0.53
MAPT P10636 1/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31664325 1.00 KDM4E (0.61) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL23277174 0.98 KDM4E (0.59) KDM4EHPGDHSD17B10HTTALDH1A1
Fluoride SCHEMBL28851572 0.98 KDM4E (0.59) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL29010714 0.87 KDM4E (0.63) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL13369192 0.85 KDM4E (0.50) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL29365231 0.83 HTT (0.78) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL3527 0.83 HTT (0.78) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL15106396 0.82 KDM4E (0.46) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL7672827 0.82 IRAK4 (0.59) KDM4EHPGDHSD17B10HTTALDH1A1
SCHEMBL28178564 0.82 SLC6A3 (0.61) KDM4EHSD17B10HTTALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2120 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122031336-A Whitening and freckle-removing composition based on multi-channel synergy and application thereof 广州诺彦生物科技有限公司 2026-05-15 CN claimed
US-20260124148-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY BHAMIS RES LABORATORY PVT LTD (IN) 2026-05-07 US claimed
US-12533321-B2 Polypeptide formulations for oral delivery Bhami's Research Laboratory, Pvt. Ltd. (IN) 2026-01-27 US claimed
EP-4601623-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2025-08-20 EP claimed
CN-118995343-A Cleaning composition and preparation method and application thereof 上海盛剑微电子有限公司 2024-11-22 CN claimed
US-20240122860-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 US claimed
US-20240122847-A1 ORAL POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 US claimed
WO-2024079738-A1 ORAL POLYPEPTIDE FORMULATIONS Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 WO claimed
WO-2024079739-A1 POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY Bhami's Research Laboratory, Pvt. Ltd. (IN) 2024-04-18 WO claimed
CN-117462452-A Cosmetic product 株式会社资生堂 2024-01-30 CN claimed
US-20060222597-A1 Buccal, polar and non-polar sprays containing propofol NOVADEL PHARMA INC. 2006-10-05 US claimed
US-20060023808-A1 Compositions, kits, and methods for calibration in mass spectrometry Life Technologies Corporation 2006-02-02 US claimed
WO-2005114220-A2 COMPOSITIONS, KITS, AND METHODS FOR CALIBRATION IN MASS SPECTROMETRY INVITROGEN CORPORATION (US) 2005-12-01 WO claimed
WO-2005105042-A1 BUCCAL, POLAR AND NON-POLAR SPRAYS CONTAINING PROPOFOL NOVADEL PHARMA INC. (US) 2005-11-10 WO claimed
US-20050118272-A1 Micronized pharmaceutical or nutraceutical powder with immediate release GALENIX INNOVATIONS (FR) 2005-06-02 US claimed
US-20050002867-A1 Buccal, polar and non-polar sprays containing propofol NOVADEL PHARMA INC. 2005-01-06 US claimed
EP-1458356-A1 MICRONIZED PHARMACEUTICAL OR NUTRACEUTICAL POWDER WITH IMMEDIATE RELEASE Besins International Belgique (BE) 2004-09-22 EP claimed
WO-2003055464-A1 MICRONIZED PHARMACEUTICAL OR NUTRACEUTICAL POWDER WITH IMMEDIATE RELEASE BESINS INTERNATIONAL BELGIQUE (BE) 2003-07-10 WO claimed
US-20030124191-A1 Use of an immediate-release powder in pharmaceutical and nutraceutical compositions GALENIX INNOVATIONS (FR) 2003-07-03 US claimed
EP-0035770-B1 AN ORALLY ADMINISTERED DRUG FORM COMPRISING A GLYCOSIDIC ANTIBIOTIC AND AN ADJUVANT INTERx RESEARCH CORPORATION (US) 1986-12-30 EP claimed