Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL1002905 | 1.00 | KDM4E (0.44) | KDM4EHPGDALDH1A1HSD17B10IRAK4 | |
| SCHEMBL730840 | 0.96 | KDM4E (0.48) | KDM4EHPGDALDH1A1HSD17B10IRAK4 | |
| Potassium Ion SCHEMBL29026645 | 0.84 | CTSD (0.56) | HPGDALDH1A1HSD17B10CTSDHTT | |
| SCHEMBL7672827 | 0.82 | IRAK4 (0.59) | KDM4EHPGDALDH1A1HSD17B10IRAK4 | |
| SCHEMBL1333594 | 0.80 | CTSD (0.56) | HPGDALDH1A1HSD17B10CTSDHTT | |
| Zinc Ion SCHEMBL10404876 | 0.80 | CTSD (0.56) | HPGDALDH1A1HSD17B10CTSDHTT | |
| SCHEMBL2514158 | 0.80 | CTSD (0.56) | KDM4EHPGDALDH1A1HSD17B10CTSD | |
| Lithium Ion SCHEMBL7961800 | 0.80 | CTSD (0.56) | HPGDALDH1A1HSD17B10CTSDHTT | |
| SCHEMBL31664325 | 0.80 | KDM4E (0.61) | KDM4EHPGDALDH1A1HSD17B10HTT | |
| SCHEMBL5459 | 0.80 | KDM4E (0.61) | KDM4EHPGDALDH1A1HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116637040-A | Tranexamic acid glutathione composite water agent and preparation method thereof | 成都卓阳生物科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-113559005-B | Tranexamic acid glutathione composite water agent and preparation method thereof | 成都卓阳生物科技有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-115252460-B | Acne-removing composition containing antibacterial peptide, and preparation method and application thereof | 媞颂日化用品(广州)有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118265517-A | Oil-in-water type emulsified cosmetic | 株式会社资生堂 | 2024-06-28 | — | — | CN | disclosed |
| CN-116637040-A | Tranexamic acid glutathione composite water agent and preparation method thereof | 成都卓阳生物科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113559005-B | Tranexamic acid glutathione composite water agent and preparation method thereof | 成都卓阳生物科技有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-111956506-B | Active ingredient fixed-point pressing release type skin care pad pasting | 珀莱雅化妆品股份有限公司 | 2022-11-08 | — | — | CN | disclosed |
| WO-2022137636-A1 | OIL-IN-WATER TYPE SUNSCREEN COSMETIC | 株式会社 資生堂 | 2022-06-30 | — | — | WO | disclosed |
| CN-114599342-A | Water-in-oil type emulsified sunscreen cosmetic | 株式会社资生堂 | 2022-06-07 | — | — | CN | disclosed |