Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670722 | 0.83 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTGAAKEAP1 | |
| SCHEMBL8064604 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CTSKHPGDMAPTKDM4E | |
| SCHEMBL8072732 | 0.75 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8072890 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8071202 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7665567 | 0.72 | MAPT (0.42) | ALDH1A1CTSKMAPTKDM4E | |
| SCHEMBL8063159 | 0.71 | KMT2A (0.46) | ALDH1A1HPGDMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11825055 | 0.70 | LTA4H (0.45) | ALDH1A1MAPTGAAKEAP1KDM4E | |
| SCHEMBL7694919 | 0.69 | MAPT (0.37) | ALDH1A1MAPTKDM4E | |
| SCHEMBL7672473 | 0.69 | RAB9A (0.53) | ALDH1A1CTSKHPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348614-B1 | PROTECTING CROPS AGAINST PLANT DISEASES | AGROGENE LTD. (IL) | 2002-02-19 | — | — | US | disclosed |
| EP-0948481-A1 | AMINOBUTYRIC ACID FUNGICIDES | Agrogene Ltd. (IL) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998029387-A1 | AMINOBUTYRIC ACID FUNGICIDES | AGROGENE LTD. (IL) | 1998-07-09 | — | — | WO | disclosed |