Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 13/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679189 | 0.92 | ADRA1D (0.43) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7675111 | 0.92 | ADRA1D (0.43) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7679689 | 0.92 | ADRA1D (0.43) | ADRA1AADRA1DADRA1B | |
| SCHEMBL5663243 | 0.73 | MTOR (0.35) | ADRA1A | |
| SCHEMBL5661778 | 0.73 | MTOR (0.35) | ADRA1A | |
| SCHEMBL7672939 | 0.72 | CYP1A2 (0.42) | — | |
| SCHEMBL7672602 | 0.72 | MCHR1 (0.40) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7748936 | 0.71 | CCR2 (0.43) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7678845 | 0.71 | MTOR (0.34) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7673189 | 0.71 | MTOR (0.34) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |