SCHEMBL767367

SCHEMBL767367

CO[SiH](OC)C(C)CC(C)OCC1CO1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4924944 0.83 SMN1; SMN2 (0.33) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL6303425 0.81 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL3723487 0.78 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL18095076 0.77 ALDH1A1 (0.40) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL12722456 0.77 ALDH1A1 (0.40) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL8435928 0.76 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL8460322 0.75 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL7907879 0.75 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL230965 0.75 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1SMN1; SMN2
SCHEMBL6310703 0.73 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115746616-A Surface-modified hollow silica particles and surface-modified hollow silica dispersion 凯斯科技股份有限公司 2023-03-07 CN claimed
US-20240228306-A9 DISPERSION OF EXFOLIATED PARTICLES OF LAYERED POLYSILICATE COMPOUND, AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2024-07-11 US disclosed
US-20240231230-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-07-11 US disclosed
US-20240201593-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-06-20 US disclosed
US-20240132365-A1 DISPERSION OF EXFOLIATED PARTICLES OF LAYERED POLYSILICATE COMPOUND, AND METHOD FOR PRODUCING SAME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2024-04-25 US disclosed
WO-2024063044-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM 日産化学株式会社 2024-03-28 WO disclosed
US-11920057-B2 Inorganic oxide particles coated with silane compound having nitrogen-containing ring and coating composition NISSAN CHEMICAL CORPORATION (JP) 2024-03-05 US disclosed
US-20240069441-A1 COMPOSITION FOR RESIST UNDERLYING FILM FORMATION NISSAN CHEMICAL CORPORATION (JP) 2024-02-29 US disclosed
WO-2024019064-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING POLYFUNCTIONAL SULFONIC ACID 日産化学株式会社 2024-01-25 WO disclosed
US-20240010872-A1 ORGANOSILICON COMPOUND, HYDROLYSIS CONDENSATION PRODUCT OF SAME, AND COATING COMPOSITION SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-11 US disclosed
EP-0992456-A1 PROCESS FOR PRODUCING COMPOSITE SOLS, COATING COMPOSITION, AND OPTICAL MEMBER Nissan Chemical Industries, Ltd. (JP) 2000-04-12 EP disclosed
US-6040372-A Hydrated zinc stannate sols, coating compositions and optical elements NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-03-21 US disclosed
US-6001164-A AS MICROFILLERS TO BE USED AS HARD COATING AGENT WITH HIGH REFRACTIVE INDEX TO BE APPLIED ON SURFACE OF PLASTIC LENSES, FILMS OR PLASTIC MOLDED PRODUCTS, OR MAY BE MIXED WITH VARIOUS RESIN EMULSIONS FOR USE AS FLAME RETARDANTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-12-14 US disclosed
EP-0927700-A1 Method of producing anhydrous zinc antimonate NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1999-07-07 EP disclosed
EP-0909784-A1 Anhydrous zinc antimonate sol and method for producing the same NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-04-21 EP disclosed
US-5891362-A DISPERSED IN LIQUID NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-04-06 US disclosed
EP-0748768-A1 Hydrated zinc stannate sols, coating compositions and optical elements NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1996-12-18 EP disclosed
EP-0526975-B1 Coating composition for optical plastic moldings ITOH OPTICAL IND (JP) 1995-07-26 EP disclosed
US-5322888-A Curable mixture of hydrolyzable silicate, epoxy-containing silane, dicarboxylic acid or anhydride, and imidazole catalyst; protective coating for optical substrate having a high refractive index; radiation resistance ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1994-06-21 US disclosed
EP-0526975-A2 Coating composition for optical plastic moldings ITOH OPTICAL INDUSTRIAL CO., LTD. (JP) 1993-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010872-A1 ORGANOSILICON COMPOUND, HYDROLYSIS CONDENSATION PRODUCT OF SAME, AND COATING COMPOSITION MCM4, ODC1, MCM6 ALDH1A1 3754/4885TSHR 4812/4885MAPK1 4124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.