Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899179 | 1.00 | HTR1A (0.32) | HTR1A | |
| SCHEMBL6898797 | 0.87 | HTR1A (0.33) | HTR1A | |
| SCHEMBL6899406 | 0.84 | KDM4E (0.34) | HTR1A | |
| SCHEMBL6895514 | 0.83 | MBOAT4 (0.33) | HTR1A | |
| SCHEMBL6891091 | 0.82 | TP53 (0.33) | HTR1A | |
| SCHEMBL6896007 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL27559938 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL6897336 | 0.81 | TP53 (0.34) | HTR1A | |
| SCHEMBL7657328 | 0.81 | TP53 (0.34) | HTR1A | |
| SCHEMBL6895866 | 0.81 | TP53 (0.34) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492370-B1 | Urea derivatives and pharmaceutical compositions thereof | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |