Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6814779 | 0.91 | MEN1 (0.47) | RORCMEN1KMT2ALMNATDP1 | |
| SCHEMBL6815087 | 0.91 | MEN1 (0.47) | RORCMEN1KMT2ALMNATDP1 | |
| SCHEMBL6814091 | 0.82 | LMNA (0.47) | RORCMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6819553 | 0.82 | MEN1 (0.46) | RORCMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6811044 | 0.79 | MEN1 (0.43) | RORCMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6816529 | 0.79 | MEN1 (0.43) | RORCMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6816236 | 0.78 | RORC (0.73) | RORCMEN1KMT2ALMNATDP1 | |
| SCHEMBL7673938 | 0.77 | ALDH1A1 (0.67) | RORCMEN1KMT2ALMNATDP1 | |
| SCHEMBL6811381 | 0.76 | PTPN1 (0.43) | RORCMEN1KMT2ALMNATDP1 | |
| SCHEMBL6816478 | 0.76 | RORC (0.53) | RORCMEN1KMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407123-B1 | VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |