Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7672849 | 0.99 | BLM (0.41) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL7667788 | 0.93 | LMNA (0.41) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL7667777 | 0.92 | LMNA (0.40) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL7673978 | 0.91 | LMNA (0.39) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL7673969 | 0.91 | LMNA (0.39) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL7672815 | 0.88 | OXTR (0.42) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| Hydrochloric Acid SCHEMBL7670137 | 0.87 | OXTR (0.41) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL7672200 | 0.86 | DRD2 (0.36) | HRH3LMNAHTTMEN1KMT2A | |
| SCHEMBL7662944 | 0.86 | HRH3 (0.39) | HRH3CYP1A2CYP3A4CYP2C19BLM | |
| SCHEMBL7671754 | 0.85 | NPC1 (0.43) | HTTMEN1KMT2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403607-B1 | ANTIULCER | Hidaka, Hiroyoshi (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1072587-A1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Hidaka, Hiroyoshi (JP) | 2001-01-31 | — | — | EP | disclosed |