SCHEMBL7674089

SCHEMBL7674089

O=c1c(Cc2cccnc2)cn2c3c(cc(OCn4nnc5ccccc54)cc13)Sc1cc(Br)ccc1-2

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTK2 Q05397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7668484 0.94 PTK2 (0.33) PTK2
SCHEMBL7666731 0.87 PTK2 (0.33) PTK2
SCHEMBL7674317 0.87 PTK2 (0.36) PTK2
SCHEMBL7669036 0.86 PTK2 (0.34) PTK2
SCHEMBL7672395 0.86 PTK2 (0.32) PTK2
SCHEMBL7662091 0.86 KCNA5 (0.34) PTK2
SCHEMBL7666498 0.86 KCNA5 (0.34) PTK2
SCHEMBL7669107 0.85 PTK2 (0.34) PTK2
SCHEMBL7672580 0.85 PKM (0.36)
SCHEMBL7664732 0.85 PTK2 (0.31) PTK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476021-B1 Compounds having cGMP-PDE inhibitory effect MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2002-11-05 US disclosed
EP-1048666-A1 NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed