Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.56 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7674144 | 1.00 | POLB (0.64) | POLBALDH1A1NPSR1NPC1GPR139 | |
| SCHEMBL7677201 | 0.85 | NPSR1 (0.70) | POLBALDH1A1NPSR1NPC1GPR139 | |
| SCHEMBL7677272 | 0.85 | NPSR1 (0.70) | POLBALDH1A1NPSR1NPC1GPR139 | |
| SCHEMBL19112871 | 0.81 | POLB (0.69) | POLBALDH1A1NPSR1NPC1GPR139 | |
| SCHEMBL30739602 | 0.81 | POLB (0.78) | POLBALDH1A1NPSR1GPR139TP53 | |
| SCHEMBL2855037 | 0.81 | POLB (0.78) | POLBALDH1A1NPSR1GPR139TP53 | |
| SCHEMBL18086855 | 0.81 | POLB (0.54) | POLBALDH1A1NPSR1NPC1GPR139 | |
| SCHEMBL18086864 | 0.81 | POLB (0.64) | POLBALDH1A1NPSR1NPC1GPR139 | |
| Hydrochloric Acid SCHEMBL18063328 | 0.80 | POLB (0.53) | POLBALDH1A1NPSR1NPC1GPR139 | |
| Hydrochloric Acid SCHEMBL18063329 | 0.80 | POLB (0.53) | POLBALDH1A1NPSR1NPC1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020052295-A1 | Diacyl derivatives of propylene diamine having herbicidal activity | MONSANTO TECHNOLOGY LLC | 2002-05-02 | — | — | US | disclosed |
| WO-2001046152-A1 | HERBICIDAL DIACYL DERIVATIVES OF PROPYLENE DIAMINE | MONSANTO TECHNOLOGY LLC (US) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052295-A1 | Diacyl derivatives of propylene diamine having herbicidal activity | DDT, SAT1, AOC1 | POLB 1606/4885ALDH1A1 232/4885NPSR1 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.