SCHEMBL7674252

SCHEMBL7674252

CC1([SiH2]c2ccc(OC/C=C/c3ccccc3)cc2)CCCCO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.40
MAOB P27338 2/20 0.40
KMT2A Q03164 2/20 0.39
PPARA Q07869 3/20 0.38
PPARG P37231 3/20 0.38
PPARD Q03181 2/20 0.38
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
RELA Q04206 1/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
THPO P40225 1/20 0.34
HIF1A Q16665 1/20 0.34
MTOR P42345 1/20 0.34
IDO1 P14902 1/20 0.34
CHRNA7 P36544 4/20 0.34
CHRNA10 Q9GZZ6 2/20 0.34
CHRNA9 Q9UGM1 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7648441 0.80 MAOB (0.42) MAOAMAOBRAB9ACYP1A2HIF1A
SCHEMBL9778963 0.76 MAOA (0.44) MAOAMAOBKMT2APPARAPPARG
SCHEMBL9778960 0.76 MAOA (0.44) MAOAMAOBKMT2APPARAPPARG
SCHEMBL251108 0.76 TRPA1 (0.30) KMT2AMEN1POLB
SCHEMBL9778573 0.73 MAOA (0.49) MAOAMAOBKMT2APPARAPPARG
SCHEMBL9778578 0.73 MAOA (0.49) MAOAMAOBKMT2APPARAPPARG
SCHEMBL9251036 0.70 MAPT (0.37) MAOBKMT2ARAB9ANPC1MEN1
SCHEMBL11426742 0.68 IDO1 (0.61) MAOAMAOBKMT2APPARAPPARG
SCHEMBL1158153 0.68 IDO1 (0.61) MAOAMAOBKMT2APPARAPPARG
SCHEMBL1158152 0.68 IDO1 (0.61) MAOAMAOBKMT2APPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002017973-A2 PREPARING STERILE ARTICLES FROM CERTAIN POLYMERS OCCIDENTAL CHEMICAL CORPORATION (US) 2002-03-07 WO disclosed