SCHEMBL251108

SCHEMBL251108

CC1([SiH2]c2ccccc2)CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26126695 0.81 SLC6A4 (0.35) MEN1KMT2AKCNH2
SCHEMBL7648441 0.81 MAOB (0.42)
SCHEMBL7674252 0.76 MAOA (0.40) MEN1POLBKMT2A
SCHEMBL11648239 0.75 AKR1C1 (0.32) MEN1POLBKMT2A
SCHEMBL10937384 0.75 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL999023 0.75 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL7839459 0.75 MEN1 (0.30) MEN1POLBKMT2A
SCHEMBL3258571 0.75 MEN1 (0.31) MEN1POLBKMT2A
SCHEMBL6536454 0.75 ALDH1A1 (0.31)
SCHEMBL9270158 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112930371-B Acrylic copolymer composition, method for preparing the same, and acrylic copolymer blend comprising the same 株式会社LG化学 2022-12-20 CN claimed
CN-115362142-A Use of substituted cinnamates as stabilizers for organic materials, stabilized organic materials, methods of stabilizing organic materials, and specific cinnamates 弗劳恩霍夫应用研究促进协会 2022-11-18 CN claimed
CN-112930371-A Acrylic copolymer composition, method for preparing the same, and acrylic copolymer blend comprising the same 株式会社LG化学 2021-06-08 CN claimed
US-10591377-B2 Pressure transfer module and pressure measuring transducer having a pressure transfer module ENDRESS+HAUSER SE+CO.KG (DE) 2020-03-17 US claimed
EP-2964181-B1 POLYMERS AND METHODS TO MITIGATE THE LOSS OF SILICONE DEPOSITION FROM KERATINOUS SUBSTRATES LUBRIZOL ADVANCED MAT INC (US) 2018-05-30 EP claimed
EP-2391664-A1 COSMETIC COMPOSITION COMPRISING AN AQUEOUS DISPERSION OF POLYSILOXANE/POLYUREA AND A SILANE AND A METHOD FOR COSMETIC TREATMENT L'Oréal (FR) 2011-12-07 EP claimed
WO-2010086568-A1 COSMETIC COMPOSITION COMPRISING AN AQUEOUS DISPERSION OF POLYSILOXANE/POLYUREA AND A SILANE AND A METHOD FOR COSMETIC TREATMENT L'OREAL (FR) 2010-08-05 WO claimed
WO-2010086563-A1 AQUEOUS COPOLYMER DISPERSION OF POLYSILOXANE/POLYUREA, COSMETIC COMPOSITION COMPRISING THE SAME METHOD FOR COSMETIC TREATMENT AND METHOD FOR PREPARATION L'OREAL (FR) 2010-08-05 WO claimed
JP-3950631-B2 2007-08-01 JP claimed
JP-2002518534-A 2002-06-25 JP claimed
EP-1093484-A1 AQUEOUS SILICONE DISPERSION, CROSSLINKABLE INTO TRANSPARENT ELASTOMER RHODIA CHIMIE (FR) 2001-04-25 EP claimed
WO-2000000163-A1 ANTIBODIES AND COMPOSITIONS FOR TOPICAL USE CONTAINING SAME L'OREAL (FR) 2000-01-06 WO claimed
WO-1999065973-A1 AQUEOUS SILICONE DISPERSION, CROSSLINKABLE INTO TRANSPARENT ELASTOMER RHODIA CHIMIE (FR) 1999-12-23 WO claimed
EP-0155051-B1 OPTICAL GLASS FIBRE WITH A POLYMER COATING AND PROCESS FOR MAKING IT Koninklijke Philips Electronics N.V. (NL) 1990-11-07 EP claimed
EP-0169592-B1 OPTICAL-GLASS FIBRE WITH A POLYMERIC COATING Koninklijke Philips Electronics N.V. (NL) 1988-03-09 EP claimed
EP-0169592-A1 Optical-glass fibre with a polymeric coating Koninklijke Philips Electronics N.V. (NL) 1986-01-29 EP claimed
EP-0155051-A1 Optical glass fibre with a polymer coating and process for making it Koninklijke Philips Electronics N.V. (NL) 1985-09-18 EP claimed
JP-1185361-A None JP disclosed
US-4038338-A NEW POLYEPOXIDE-POLYSILOXANE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed
US-4016328-A SILICONE RESIN, SILICONE GUM, 2,4-DICHLOROBENZOYL PEROXIDE AS CURING AGENT GENERAL ELECTRIC COMPANY (US) 1977-04-05 US disclosed