Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002930 | 1.00 | RAB9A (0.53) | RAB9AMAPTNPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL7676325 | 0.81 | LY96 (0.54) | RAB9AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL7674085 | 0.81 | KMT2A (0.55) | MAPTNPC1MEN1KMT2ANFKB1 | |
| SCHEMBL7003196 | 0.81 | LY96 (0.54) | RAB9AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL7674081 | 0.81 | KMT2A (0.55) | MAPTNPC1MEN1KMT2ANFKB1 | |
| SCHEMBL7676274 | 0.80 | FLT3 (0.64) | RAB9AMAPTNPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL7005500 | 0.80 | FLT3 (0.64) | RAB9AMAPTNPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL8635621 | 0.75 | TRPA1 (0.65) | RAB9AMAPTNPC1SMN1; SMN2NFE2L2 | |
| SCHEMBL6997417 | 0.75 | MAPT (0.49) | RAB9AMAPTNPC1SMN1; SMN2MEN1 | |
| SCHEMBL8635625 | 0.75 | TRPA1 (0.65) | RAB9AMAPTNPC1SMN1; SMN2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | claimed |