Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675797 | 0.87 | FDPS (0.35) | — | |
| SCHEMBL11195464 | 0.79 | MMP1 (0.34) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL27837451 | 0.79 | — | — | |
| SCHEMBL7673042 | 0.78 | FDPS (0.31) | — | |
| SCHEMBL7672351 | 0.77 | — | — | |
| SCHEMBL7677092 | 0.77 | MMP1 (0.32) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL7679803 | 0.74 | MMP1 (0.33) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL28258943 | 0.73 | ALDH1A1 (0.36) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL27927495 | 0.73 | MMP1 (0.31) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL3101607 | 0.71 | ALDH1A1 (0.39) | MMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | disclosed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |