Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668730 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNARAB9AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL5967015 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAMAPTNPSR1TSHR | |
| Hydrochloric Acid SCHEMBL6246577 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9AKMT2ANPSR1 | |
| SCHEMBL28046867 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNARAB9AMAPTHPGD | |
| SCHEMBL31138116 | 0.80 | USP2 (0.47) | ALDH1A1LMNAKMT2ANPSR1TSHR | |
| SCHEMBL2961656 | 0.80 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9AMAPTHPGD | |
| SCHEMBL2960264 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNARAB9AMAPTHPGD | |
| SCHEMBL15049655 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNARAB9AMAPTKMT2A | |
| SCHEMBL7288389 | 0.76 | ANPEP (0.56) | ALDH1A1LMNARAB9AMAPTKMT2A | |
| SCHEMBL5533637 | 0.76 | ALDH1A1 (0.61) | ALDH1A1LMNARAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403644-B1 | FOR PREVENTION AND/OR TREATMENT OF DISEASES INDUCED BY OVEREXPRESSION AND EXCESS ACTIVITY OF MATRIX METALLOPROTEINASE; FOR EXAMPLE, RHEUMATOID, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-06-11 | — | — | US | claimed |
| US-6177466-B1 | Sulfonylamino acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-23 | — | — | US | disclosed |