Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3969603 | 0.81 | L3MBTL1 (0.59) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL16879993 | 0.81 | ALDH1A1 (0.58) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL28046877 | 0.80 | L3MBTL1 (0.46) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL7674646 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL11668730 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL27746658 | 0.79 | LMNA (0.56) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL5718257 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL10505588 | 0.78 | ALDH1A1 (0.67) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL2961656 | 0.77 | ALDH1A1 (0.50) | ALDH1A1LMNARAB9ANPSR1MAPT | |
| SCHEMBL28376968 | 0.77 | LMNA (0.54) | ALDH1A1LMNARAB9ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130834-B | A kind of preparation method of β amidos alpha amino acid ester derivative | 中国科学院兰州化学物理研究所 | 2017-06-23 | — | — | CN | disclosed |
| CN-105130834-A | Preparation method of beta-amido-alpha-amino-acid ester derivative | LANZHOU CHEM PHYS INST | 2015-12-09 | — | — | CN | disclosed |