Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681510 | 0.78 | — | — | |
| SCHEMBL4701549 | 0.78 | PKM (0.48) | HPGDALDH1A1PKMPOLBCYP2C19 | |
| SCHEMBL7353467 | 0.77 | HPGD (0.60) | HPGDALDH1A1PKMPOLBCYP2C19 | |
| SCHEMBL3563280 | 0.77 | HPGD (0.47) | HPGDALDH1A1PKMPOLBCYP2C19 | |
| SCHEMBL4755632 | 0.77 | ALDH1A1 (0.47) | HPGDALDH1A1PKMPOLBCYP2C19 | |
| Hydrochloric Acid SCHEMBL5198544 | 0.76 | HPGD (0.55) | HPGDALDH1A1PKMPOLBCYP2C19 | |
| Methyl Alcohol SCHEMBL11407062 | 0.76 | CYP2C19 (0.55) | HPGDALDH1A1PKMPOLBCYP2C19 | |
| SCHEMBL3757996 | 0.75 | — | — | |
| SCHEMBL621289 | 0.75 | — | — | |
| SCHEMBL4682346 | 0.75 | TAAR1 (0.47) | HPGDALDH1A1POLBCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923539-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2002-06-05 | — | — | EP | claimed |