Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816200 | 0.94 | GRM4 (0.56) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7682760 | 0.82 | FADS1 (0.55) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6815195 | 0.81 | KMT2A (0.61) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6815929 | 0.80 | GRM4 (0.62) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL7904791 | 0.79 | ALDH1A1 (0.57) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6816503 | 0.79 | KMT2A (0.61) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6814828 | 0.79 | GRM4 (0.64) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6816208 | 0.79 | GRM4 (0.51) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6815054 | 0.78 | GRM4 (0.58) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6815767 | 0.78 | KMT2A (0.74) | GRM4ALDH1A1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407123-B1 | VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |