Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815015 | 0.91 | RAB9A (0.65) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL7682760 | 0.81 | FADS1 (0.55) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL7666799 | 0.81 | KMT2A (0.57) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL6819355 | 0.80 | MAPK1 (0.66) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL6815767 | 0.79 | KMT2A (0.74) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL7904734 | 0.79 | MEN1 (0.65) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL7671864 | 0.79 | KMT2A (0.52) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL7674945 | 0.79 | GRM4 (0.54) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL6815889 | 0.79 | KMT2A (0.86) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL7665429 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207715-B1 | USEFUL IN THERAPY OF DISEASES ASSOCIATED WITH HERPES VIRUSES INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES-6 AND -7, AND KAPOSI HERPES VIRUS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-27 | — | — | US | disclosed |