Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675256 | 0.86 | ATM (0.50) | CTSBCTSLCTSSCTSKMEN1 | |
| SCHEMBL3737347 | 0.81 | CTSL (0.55) | CTSBCTSLCTSSCTSKMEN1 | |
| SCHEMBL3729660 | 0.81 | CTSL (0.56) | CTSBCTSLCTSSCTSKMEN1 | |
| SCHEMBL14728306 | 0.80 | CTSL (0.58) | CTSBCTSLCTSSCTSKMEN1 | |
| SCHEMBL12493740 | 0.80 | CTSK (0.56) | CTSBCTSLCTSSCTSKSYK | |
| SCHEMBL12493735 | 0.80 | CTSK (0.56) | CTSBCTSLCTSSCTSKSYK | |
| SCHEMBL3728346 | 0.80 | CTSK (0.55) | CTSBCTSLCTSSCTSKSYK | |
| SCHEMBL20885259 | 0.79 | SYK (0.59) | CTSBCTSLCTSSCTSKSYK | |
| SCHEMBL11657615 | 0.79 | SYK (0.59) | CTSBCTSLCTSSCTSKSYK | |
| SCHEMBL3725467 | 0.79 | CTSL (0.57) | CTSBCTSLCTSSCTSKCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150956-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047561-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2000-08-17 | — | — | WO | disclosed |