Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677389 | 0.86 | FDPS (0.41) | FDPS | |
| SCHEMBL7679803 | 0.84 | MMP1 (0.33) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL7678871 | 0.79 | FDPS (0.36) | FDPS | |
| SCHEMBL7675416 | 0.74 | — | — | |
| SCHEMBL7675687 | 0.73 | MMP1 (0.34) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL2231053 | 0.72 | — | — | |
| SCHEMBL8114586 | 0.70 | MMP1 (0.31) | MMP1MMP2MMP3MMP8 | |
| SCHEMBL7678001 | 0.70 | FDPS (0.38) | FDPS | |
| SCHEMBL20707748 | 0.69 | MMP1 (0.33) | MMP1MMP2MMP3MMP8CA12 | |
| SCHEMBL7675546 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | disclosed |