Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23918756 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL6170021 | 0.69 | RAB9A (0.54) | ALDH1A1KDM4ECNR2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL18730111 | 0.69 | DDB1 (0.50) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL6171530 | 0.69 | MEN1 (0.51) | ALDH1A1CNR2NPC1RAB9AMEN1 | |
| SCHEMBL16827699 | 0.68 | CREBBP (0.51) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL3648379 | 0.67 | PARP10 (0.66) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL24604360 | 0.66 | KDM5B (0.49) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL10941122 | 0.66 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL14886589 | 0.66 | TSHR (0.67) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL10939620 | 0.65 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6352985-B1 | CARDIOVASCULAR DISORDERS OR GASTROINTESTINAL DISORDERS, DIABETES (TYPE II DIABETES), DIABETIC COMPLICATIONS METHOD FOR LOWERING THE BLOOD SUGAR LEVEL OF A PATIENT, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6166219-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0882718-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |