Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728471 | 0.82 | — | — | |
| SCHEMBL160626 | 0.79 | CYP3A4 (0.38) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL1897709 | 0.75 | CYP3A4 (0.35) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL15850523 | 0.73 | KIF11 (0.44) | KIF11GPR3 | |
| SCHEMBL13933285 | 0.73 | KIF11 (0.32) | KIF11GPR3 | |
| SCHEMBL10347965 | 0.72 | TDP1 (0.39) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL424482 | 0.72 | IDO1 (0.39) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL4462791 | 0.72 | KIF11 (0.45) | KIF11CYP3A4TRPA1TDP1 | |
| SCHEMBL30438763 | 0.72 | IDO1 (0.39) | CYP3A4TRPA1ALDH1A1HPGDTDP1 | |
| SCHEMBL29648906 | 0.72 | MAPK1 (0.44) | KIF11CYP3A4TRPA1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444616-B1 | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-03 | — | — | US | disclosed |
| US-6130225-A | Substituted p-trifluoromethylphenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-10 | — | — | US | disclosed |
| EP-0923562-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AG (DE) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006706-A1 | SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-19 | — | — | WO | disclosed |
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |
| EP-0246061-A2 | A benzoylurea derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |