Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 4/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563164 | 0.93 | OXTR (0.39) | OXTRAVPR1AHTTAPLNRGRIN1 | |
| SCHEMBL7679942 | 0.90 | HTT (0.37) | OXTRAVPR1AHTTAPLNRGRIN1 | |
| SCHEMBL7682679 | 0.89 | OXTR (0.39) | OXTRAVPR1AHTTAPLNRGRIN1 | |
| SCHEMBL7680198 | 0.88 | OXTR (0.38) | OXTRAVPR1AHTTAPLNRGRIN1 | |
| SCHEMBL6678095 | 0.77 | GRIN1 (0.36) | OXTRAVPR1AGRIN1GRIN2DGRIN3B | |
| Water SCHEMBL6681370 | 0.76 | GRIN1 (0.35) | OXTRAVPR1AGRIN1GRIN2DGRIN3B | |
| SCHEMBL7676400 | 0.75 | OXTR (0.41) | OXTRAVPR1AHTTAPLNRTSHR | |
| SCHEMBL6678132 | 0.70 | OXTR (0.41) | OXTRAVPR1AHTTAPLNRTSHR | |
| SCHEMBL27541050 | 0.69 | APLNR (0.41) | OXTRAVPR1AHTTAPLNRMAPK1 | |
| SCHEMBL7677312 | 0.68 | OXTR (0.41) | OXTRAVPR1AHTTAPLNRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | disclosed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | disclosed |