Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | APLNR | P35414 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678132 | 0.93 | OXTR (0.41) | OXTRAVPR1AAPLNRHTTMEN1 | |
| SCHEMBL7676400 | 0.89 | OXTR (0.41) | OXTRAVPR1AAPLNRHTTMEN1 | |
| SCHEMBL27541050 | 0.87 | APLNR (0.41) | OXTRAVPR1AAPLNRHTTMEN1 | |
| SCHEMBL7678750 | 0.83 | APLNR (0.39) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL27413983 | 0.82 | APLNR (0.39) | OXTRAVPR1AAPLNRMEN1KMT2A | |
| SCHEMBL7682650 | 0.82 | APLNR (0.38) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL7681550 | 0.78 | APLNR (0.41) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL7674184 | 0.78 | SLC2A1 (0.37) | APLNRHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL27489462 | 0.77 | APLNR (0.41) | APLNRHTTMEN1KMT2AMAPK1 | |
| SCHEMBL7682679 | 0.75 | OXTR (0.39) | OXTRAVPR1AAPLNRHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103770-C | Quinoxalinediones | PFIZER RES AND DEV CO N V S A (IE) | 2003-03-26 | — | — | CN | disclosed |
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | disclosed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | disclosed |