Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.48 |
| ▸ | PDE4A | P27815 | 16/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 16/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.46 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336596 | 0.91 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7337524 | 0.87 | MPO (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8655603 | 0.85 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7089270 | 0.83 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7335045 | 0.79 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7738930 | 0.79 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6675074 | 0.79 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7683789 | 0.77 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7093510 | 0.77 | MTNR1A (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7092998 | 0.76 | PDE4B (0.60) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066641-A | PHOSPHODIESTERASES AS MOLECULAR TARGETS FOR ANTI-ASTHMATIC AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-05-23 | — | — | US | claimed |
| EP-0814809-A4 | ARYL THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | claimed |
| EP-0814809-A1 | ARYL THIOXANTHINES | Euroceltique S.A. (LU) | 1998-01-07 | — | — | EP | claimed |
| WO-1996018399-A1 | ARYL THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | claimed |
| US-6440979-B1 | Aryl isoguanines | EURO-CELTIQUE, S.A. (LU) | 2002-08-27 | — | — | US | disclosed |
| US-6090816-A | ANTIASTHMA AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-07-18 | — | — | US | disclosed |
| US-6066641-A | PHOSPHODIESTERASES AS MOLECULAR TARGETS FOR ANTI-ASTHMATIC AGENTS | EURO-CELTIQUE S.A. (LU) | 2000-05-23 | — | — | US | disclosed |
| EP-0814809-A4 | ARYL THIOXANTHINES | EURO CELTIQUE SA (LU) | 1998-04-01 | — | — | EP | disclosed |
| EP-0814809-A1 | ARYL THIOXANTHINES | Euroceltique S.A. (LU) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996018399-A1 | ARYL THIOXANTHINES | EURO-CELTIQUE, S.A. (LU) | 1996-06-20 | — | — | WO | disclosed |