Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677879 | 0.80 | MEN1 (0.67) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL7674900 | 0.80 | MEN1 (0.49) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7677332 | 0.77 | GFER (0.74) | KMT2AMAPTSMN1; SMN2ALDH1A1FAAH | |
| SCHEMBL3992783 | 0.76 | GABRP (0.54) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL14521463 | 0.75 | KMT2A (0.65) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7677361 | 0.75 | SMN1; SMN2 (0.50) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7678788 | 0.74 | POLB (0.48) | KMT2AMAPTALDH1A1MEN1KDM4E | |
| SCHEMBL29111920 | 0.74 | KMT2A (0.64) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30701089 | 0.74 | KMT2A (0.64) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29111823 | 0.74 | KMT2A (0.64) | KMT2AMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |