Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563351 | 0.86 | MMP9 (0.56) | MEN1KMT2AMGAMGAASI | |
| SCHEMBL7675824 | 0.82 | MMP9 (0.58) | MEN1KMT2AL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL7671952 | 0.81 | MMP9 (0.47) | MEN1KMT2AGAAMMP9MMP8 | |
| SCHEMBL27946627 | 0.81 | SRC (0.53) | MEN1KMT2AMGAMGAASI | |
| SCHEMBL7677326 | 0.80 | KMT2A (0.54) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7674910 | 0.78 | MAPT (0.63) | MEN1KMT2AGAAL3MBTL1MAPT | |
| SCHEMBL7676891 | 0.77 | MMP9 (0.43) | MEN1KMT2AMGAMGAASI | |
| SCHEMBL13763316 | 0.77 | GAA (0.51) | MEN1KMT2AMGAMGAASI | |
| SCHEMBL21399724 | 0.77 | GUSB (0.54) | MEN1KMT2AMGAMGAASI | |
| SCHEMBL31108453 | 0.77 | GUSB (0.54) | MEN1KMT2AMGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |