Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671378 | 0.83 | MAPT (0.65) | SMN1; SMN2GAARAB9AMEN1KMT2A | |
| SCHEMBL7677879 | 0.82 | MEN1 (0.67) | RAB9AMEN1KMT2AMAPTTSHR | |
| SCHEMBL7678788 | 0.77 | POLB (0.48) | GAAMEN1KMT2AMAPTTSHR | |
| SCHEMBL3992783 | 0.76 | GABRP (0.54) | GAAMEN1KMT2AMAPTTSHR | |
| SCHEMBL7677326 | 0.75 | KMT2A (0.54) | SMN1; SMN2RAB9AMEN1KMT2AMAPT | |
| SCHEMBL7677369 | 0.75 | GFER (0.65) | SMN1; SMN2GAARAB9AMEN1KMT2A | |
| SCHEMBL7904577 | 0.75 | ADAM17 (0.64) | SMN1; SMN2RAB9AKMT2AADAM17MAPT | |
| SCHEMBL7671803 | 0.74 | RAB9A (0.50) | RAB9AMEN1KMT2AMAPTTSHR | |
| SCHEMBL7678629 | 0.74 | MMP2 (0.50) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4001238 | 0.74 | GPR84 (0.54) | GAAMEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |