Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080387 | 1.00 | KMT2A (0.35) | KMT2AKDM4EPOLBNPSR1HTT | |
| SCHEMBL7677689 | 0.91 | RAB9A (0.33) | RAB9A | |
| SCHEMBL7684458 | 0.81 | RAB9A (0.33) | RAB9A | |
| SCHEMBL7684877 | 0.81 | RAB9A (0.31) | RAB9A | |
| SCHEMBL7961405 | 0.78 | MAOB (0.35) | KMT2AKDM4EPOLBNPSR1HTT | |
| SCHEMBL7961402 | 0.78 | MAOB (0.35) | KMT2AKDM4EPOLBNPSR1HTT | |
| SCHEMBL6559723 | 0.77 | LMNA (0.34) | KMT2AKDM4EHTTLMNAMEN1 | |
| SCHEMBL8026715 | 0.76 | HIF1A (0.47) | KMT2AKDM4EPOLBNPSR1HTT | |
| SCHEMBL7683910 | 0.75 | ALDH1A1 (0.32) | ALDH1A1CTNNB1WNT3A | |
| SCHEMBL7661588 | 0.71 | KMT2A (0.46) | KMT2AKDM4EPOLBNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420362-B1 | Azines containing the 5,6-di-hydro-(1,4,2) dioxazine-3-yl group and the use thereof as fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |