Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447649 | 0.79 | HTR6 (0.47) | HTR6HTR1AIDO1MTNR1AMTNR1B | |
| SCHEMBL3100368 | 0.78 | HTR1A (0.55) | HTR6HTR1AIDO1SIGMAR1PRCP | |
| SCHEMBL7680750 | 0.76 | HTR6 (0.42) | HTR6IDO1MTNR1AMTNR1BPDPK1 | |
| SCHEMBL28768460 | 0.75 | HTR6 (0.50) | HTR6IDO1MTNR1AMTNR1BPDPK1 | |
| SCHEMBL30462590 | 0.74 | IDO1 (0.54) | HTR1AIDO1SIGMAR1PRCPPDPK1 | |
| SCHEMBL3980047 | 0.74 | HTR6 (0.46) | HTR6HTR1AIDO1MTNR1AMTNR1B | |
| SCHEMBL19617864 | 0.73 | HTR6 (0.42) | HTR6IDO1MTNR1AMTNR1BPDPK1 | |
| SCHEMBL1567129 | 0.72 | HTR1A (0.47) | HTR1AIDO1SIGMAR1PRCPPDPK1 | |
| SCHEMBL29393411 | 0.72 | HTR1A (0.47) | HTR1AIDO1SIGMAR1PRCPPDPK1 | |
| SCHEMBL1567192 | 0.72 | HTR6 (0.54) | HTR6HTR1AIDO1MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |