SCHEMBL7677978

SCHEMBL7677978

CCCCC(Cl)N(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10478914 0.97 DNM1 (0.36)
Hydrochloric Acid SCHEMBL31303727 0.90 DNM1 (0.39)
SCHEMBL27839880 0.90 LMNA (0.41)
SCHEMBL29080710 0.90 LMNA (0.41)
Hydrochloric Acid SCHEMBL30570482 0.87 DNM1 (0.42)
SCHEMBL8108578 0.82
SCHEMBL2270019 0.82
Hydrochloric Acid SCHEMBL7371837 0.80
SCHEMBL8099290 0.76 DNM1 (0.36)
SCHEMBL22440433 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111393399-B Prodrugs of mycophenolic acid and method for preparing same 广州润尔眼科生物科技有限公司 2023-05-30 CN disclosed
US-20220002248-A1 MDM2 INHIBITOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) 2022-01-06 US disclosed
EP-3858812-A1 MDM2 INHIBITOR, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF Shanghai Longwood Biopharmaceuticals Co., Ltd. (CN) 2021-08-04 EP disclosed
CN-113185424-A Method for removing trace DMAc in DMF (dimethyl formamide) 安徽金禾实业股份有限公司 2021-07-30 CN disclosed
CN-108409697-A A kind of highly selective hypochlorous probe of detection of hypersensitive 济南大学 2018-08-17 CN disclosed
CN-107935868-A A kind of crystal form of 5 hydroxytryptamine reuptake inhibithors and preparation method thereof 广州白云山医药集团股份有限公司白云山制药总厂 2018-04-20 CN disclosed
US-6489337-B1 TREATMENT OF ALZHEIMER'S DISEASE, EPILEPSY, EATING DISORDERS, LEARNING AND MEMORY DISORDERS, MIGRAINE, SLEEP/WAKE DISORDERS, ALLERGIC RHINITIS, SCHIZOPHRENIA, MILD COGNITIVE IMPAIRMENT, AND ASTHMA ORTHO-MCNEIL PHARMACEUTICAL, INC. 2002-12-03 US disclosed
WO-2001074813-A2 METHOD FOR USING 2- OR 3-ARYL SUBSTITUTED IMIDAZO[1,2-a] PYRIDINES AS H3 ANTAGONISTS ORTHO MCNEIL PHARMACEUTICAL, INC. (US) 2001-10-11 WO disclosed
EP-1056744-A1 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES Aventis Pharmaceuticals Inc. (US) 2000-12-06 EP disclosed
WO-1999043675-A1 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES AVENTIS PHARMACEUTICALS INC. (US) 1999-09-02 WO disclosed
US-4871745-A LOCAL ANESTHETICS ORTHO PHARMACEUTICAL CORPORATION (US) 1989-10-03 US disclosed
US-4791117-A LOCAL ANTESTHETICS, ANTISECRETORY AGENTS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-12-13 US disclosed
EP-0261912-A2 2- or 3- Aryl substituted imidazo [1,2-a] pyridines ORTHO PHARMACEUTICAL CORPORATION (US) 1988-03-30 EP disclosed
US-4727145-A LOCAL ANESTHETICS ORTHO PHARMACEUTICAL CORPORATION (US) 1988-02-23 US disclosed