Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.42 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | FLT1 | P17948 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | INSR | P06213 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672106 | 0.87 | DRD2 (0.39) | KDRMEN1KMT2AEGFRINSR | |
| SCHEMBL7677729 | 0.86 | KDR (0.35) | FAAHKDRFLT1EGFRINSR | |
| SCHEMBL7675307 | 0.83 | FLT1 (0.42) | KDRFLT1MEN1KMT2A | |
| SCHEMBL7675572 | 0.83 | FLT1 (0.42) | KDRFLT1MEN1KMT2A | |
| SCHEMBL7670964 | 0.82 | MEN1 (0.45) | KDRFLT1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7672407 | 0.82 | MEN1 (0.44) | KDRFLT1MEN1KMT2A | |
| SCHEMBL7671243 | 0.82 | MEN1 (0.44) | KDRFLT1MEN1KMT2A | |
| SCHEMBL7669698 | 0.81 | FLT1 (0.43) | KDRFLT1MEN1KMT2A | |
| SCHEMBL7679446 | 0.80 | MEN1 (0.46) | KDRFLT1MEN1KMT2A | |
| SCHEMBL7678998 | 0.79 | MEN1 (0.43) | KDRFLT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479514-B1 | FOR THE CONTROL OF HELICOBACTER BACTERIA IN INFECTED PATIENTS | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1086094-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999061438-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |