Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | FLT1 | P17948 | 5/20 | 0.35 |
| ▸ | FAAH | O00519 | 7/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678516 | 0.86 | FAAH (0.42) | KDRFLT1FAAHIGF1REGFR | |
| SCHEMBL6868402 | 0.82 | GRM2 (0.31) | GRM2 | |
| SCHEMBL7671316 | 0.79 | MEN1 (0.32) | KDRFLT1FAAHDHFR | |
| SCHEMBL7670896 | 0.78 | MEN1 (0.35) | KDRFLT1DHFR | |
| SCHEMBL7672106 | 0.77 | DRD2 (0.39) | KDRIGF1REGFRINSRMET | |
| SCHEMBL7677581 | 0.74 | MEN1 (0.33) | KDRFLT1HTR2BDHFR | |
| SCHEMBL7675572 | 0.74 | FLT1 (0.42) | KDRFLT1DHFR | |
| SCHEMBL7675307 | 0.74 | FLT1 (0.42) | KDRFLT1DHFR | |
| SCHEMBL7670964 | 0.73 | MEN1 (0.45) | KDRFLT1DHFR | |
| SCHEMBL7671243 | 0.73 | MEN1 (0.44) | KDRFLT1DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479514-B1 | FOR THE CONTROL OF HELICOBACTER BACTERIA IN INFECTED PATIENTS | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |